Article
Genome-wide association identifies a deletion in the 3' untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy.
Human genetics - 1 Sept 2010
Meurs Kathryn M, Mauceli Evan, Lahmers Sunshine, Acland Gregory M, White Stephen N, Lindblad-Toh Kerstin
Abstract excerpt
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a familial cardiac disease characterized by ventricular arrhythmias and sudden cardiac death. It is most frequently inherited as an autosomal dominant trait with incomplete and age-related penetrance and variable clinical expression. The human disease is most commonly associated with a causative mutation in one of several genes encoding desmosomal...
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