Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP1A1 gene polymorphisms as a risk factor for pterygium.

Molecular vision - 9 Jun 2010

Young Chi-Hsien, Lo Yu-Lun, Tsai Yi-Yu, Shih Tung-Sheng, Lee Huei, Cheng Ya-Wen

Abstract excerpt

PURPOSE: Both cytochrome P4501A1 (CYP1A1) and glutathione S-transferase M1 (GSTM1) have been demonstrated to be involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs). BaP 7,8-diol 9,10-epoxide (BPDE), an ultimate metabolite of benzo(a)pyrene (BaP), attacks deoxyguanosine to form a BPDE-N2-dG adduct resulting in p53 gene mutations. Our previous report indicated that BPDE-like DNA adduct levels in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Cytochrome P-450 CYP1A1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GSTM1 gene

Share to Genetic Predisposition to Disease

Share to Glutathione Transferase

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20596254
PMCID: PMC2893055

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP1A1 gene polymorphisms as a risk factor for pterygium.PMID 20596254Read ↗

An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium.Semantic proximity Read ↗

CYP1A1 protein activity is associated with allelic variation in pterygium tissues and cells.Semantic proximity Read ↗

Analysis of the GSTM1-null polymorphism in patients with pterygium from Goiânia, Goiás Brazil.Semantic proximity Read ↗

XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.Semantic proximity Read ↗

Pterygium and genetic polymorphisms of the DNA repair enzymes XRCC1, XPA, and XPD.Semantic proximity Read ↗

The Significant Association of MMP-1 Genotypes With Taiwan Pterygium.Semantic proximity Read ↗

Pterygium and genetic polymorphism of DNA double strand break repair gene Ku70.Semantic proximity Read ↗

Null type of glutathione S-transferase M1 polymorphism is associated with early onset pterygium.Semantic proximity Read ↗

Revealing the Association of LIG1 Genetic Variants With Pterygium Susceptibility and Demographic Characteristics in a Taiwanese Population.Semantic proximity Read ↗

Mechanisms and biomarker candidates in pterygium developmentSemantic proximity Read ↗

Impacts of Matrix Metalloproteinase-11 Genotypes on Pterygium Risk.Semantic proximity Read ↗

Pterygium in patients from Goiânia, Goiás, Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.