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Article

Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2010

Enevold Christian, Oturai Annette B, Sørensen Per Soelberg, Ryder Lars P, Koch-Henriksen Nils, Bendtzen Klaus

Abstract excerpt

BACKGROUND: Interferon-beta therapy of patients with relapsing-remitting multiple sclerosis involves repeated 'immunizations' with exogenous protein solutions. Innate pattern recognition receptors play an important role in immune responses towards foreign substances and may thus be related to tre...

Read the complete abstract on PubMed

Topics

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Share to DEAD Box Protein 58
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-Induced Helicase, IFIH1

Share to Interferon Type I

Share to Multiple Sclerosis, Relapsing-Remitting

Share to Nod1 Signaling Adaptor Protein

Share to Receptor, Interferon alpha-beta

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Source

Identifiers

PMID: 20595247
DOI: 10.1177/1352458510373264

Genes

NOD2
TLR6
NOD1
TLR2
TLR4
TLR7
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20595247-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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