Article
The (r)evolution of cancer genetics.
BMC biology - 11 Jun 2010
Ciccarelli Francesca D
Abstract excerpt
The identification of an increasing number of cancer genes is opening up unexpected scenarios in cancer genetics. When analyzed for their systemic properties, these genes show a general fragility towards perturbation. A recent paper published in BMC Biology shows how the founder domains of known cancer genes emerged at two macroevolutionary transitions - the advent of the first cell and the transition to metazoan...
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