Article
Overexpression of polycomb protein BMI-1 in human specimens of breast, ovarian, endometrial and cervical cancer.
Anticancer research - 1 May 2010
Honig A, Weidler C, Häusler S, Krockenberger M, Buchholz S, Köster F, Segerer S E, Dietl J, Engel J B
Abstract excerpt
INTRODUCTION: The polycomb group (PcG) proteins form chromatin-modifying complexes that are commonly deregulated in cancer. The PcG protein BMI-I is overexpressed by various tumours and thus may contribute to malignant transformation. The current study investigated the expression of BMI-I in human specimens of breast, ovarian, endometrial and cervical cancer. MATERIALS AND METHODS: Expression of BMI-I was...
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