Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction and Inhibition of Type I Interferon Responses by Distinct Components of Lymphocytic Choriomeningitis Virus

1 Jul 2010

Abstract excerpt

Type I interferons (IFNs) play a critical role in the host defense against viruses. Lymphocytic choriomeningitis virus (LCMV) infection induces robust type I IFN production in its natural host, the mouse. However, the mechanisms underlying the induction of type I IFNs in response to LCMV infection have not yet been clearly defined. In the present study, we demonstrate that IRF7 is required for both the early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20592086
DOI: 10.1128/jvi.00155-10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction and Inhibition of Type I Interferon Responses by Distinct Components of Lymphocytic Choriomeningitis VirusPMID 20592086Read ↗

Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVSSemantic proximity Read ↗

Inhibition of the Type I Interferon Response by the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis VirusSemantic proximity Read ↗

Activation of Protein Kinase R (PKR) Plays a Pro-Viral Role in Mammarenavirus Infected CellsSemantic proximity Read ↗

Activation of protein kinase receptor (PKR) plays a pro-viral role in mammarenavirus-infected cellsSemantic proximity Read ↗

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells.Semantic proximity Read ↗

Antiviral defense: interferons and beyondSemantic proximity Read ↗

The Z Proteins of Pathogenic but Not Nonpathogenic Arenaviruses Inhibit RIG-i-Like Receptor-Dependent Interferon ProductionSemantic proximity Read ↗

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5Semantic proximity Read ↗

RIG-I and dsRNA-Induced IFNβ ActivationSemantic proximity Read ↗

Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human CellsSemantic proximity Read ↗

The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-ISemantic proximity Read ↗

Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus ReplicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.