Article
Simple genomes, complex interactions: epistasis in RNA virus.
Chaos (Woodbury, N.Y.) - 1 Jun 2010
Elena Santiago F, Solé Ricard V, Sardanyés Josep
Abstract excerpt
Owed to their reduced size and low number of proteins encoded, RNA viruses and other subviral pathogens are often considered as being genetically too simple. However, this structural simplicity also creates the necessity for viral RNA sequences to encode for more than one protein and for proteins to carry out multiple functions, all together resulting in complex patterns of genetic interactions. In this work we...
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