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Article

Potential for evolution of complex defense strategies in a multi-scale model of virus-host coevolution.

BMC evolutionary biology - 26 Oct 2016

Shin Jeewoen, MacCarthy Thomas

Abstract excerpt

BACKGROUND: Host resistance and viral pathogenicity are determined by molecular interactions that are part of the evolutionary arms race between viruses and their hosts. Viruses are obligate intracellular parasites and entry to the host cell is the first step of any virus infection. Commonly, viruses enter host cells by binding cell surface receptors. We adopt a computational modeling approach to study the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27784264
DOI: 10.1186/s12862-016-0804-z
PMCID: PMC5080737

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