Autophagy and adaptive immunity

doi:10.1111/j.1365-2567.2010.03321.x

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Article

Autophagy and adaptive immunity

25 Jun 2010

Abstract excerpt

Autophagy plays an important role in maintaining intracellular homeostasis by promoting the transit of cytoplasmic material, such as proteins, organelles and pathogens, for degradation within acidic organelles. Yet, in immune cells, autophagy pathways serve an additional role in facilitating intracellular surveillance for pathogens and changes in self. Autophagy pathways can modulate key steps in the development...

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PMID: 20586810
DOI: 10.1111/j.1365-2567.2010.03321.x

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