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Autophagy, immunity and human disease

13 Oct 2009

Abstract excerpt

PURPOSE OF REVIEW: To give an overview of autophagy and its effects on innate and adaptive immunity and touch on some of the roles of autophagy in disease. RECENT FINDINGS: Precise regulation of autophagy is necessary to maintain metabolic equilibrium, immune homeostasis, delineate cell fate and influence host cell responses to cytosolic pathogens. A growing number of studies have implicated that inactivation of...

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PMID: 19826372
DOI: 10.1097/mog.0b013e32833104f1

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