Multiple regulatory and effector roles of autophagy in immunity.

Abstract excerpt

Autophagy is a cytoplasmic homeostasis pathway, enabling cells to digest their own cytosol, remove toxic protein aggregates, and eliminate defective or surplus organelles. A plenitude of studies has now expanded roles of autophagy to both effector and regulatory functions in innate and adaptive immunity. In its role of an immunological effector, autophagy plays many parts: (i) In its most primeval manifestation,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Crohn Disease
• Share to Antigen Presentation
• Share to Autophagy