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Article

Web-based, participant-driven studies yield novel genetic associations for common traits.

PLoS genetics - 24 Jun 2010

Eriksson Nicholas, Macpherson J Michael, Tung Joyce Y, Hon Lawrence S, Naughton Brian, Saxonov Serge, Avey Linda, Wojcicki Anne, Pe'er Itsik, Mountain Joanna

Abstract excerpt

Despite the recent rapid growth in genome-wide data, much of human variation remains entirely unexplained. A significant challenge in the pursuit of the genetic basis for variation in common human traits is the efficient, coordinated collection of genotype and phenotype data. We have developed a novel research framework that facilitates the parallel study of a wide assortment of traits within a single cohort. The...

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Identifiers

PMID: 20585627
DOI: 10.1371/journal.pgen.1000993
PMCID: PMC2891811

Genes

ASIP
BNC2
HERC2
MC1R
NR2F2
OCA2
OR2M7
SLC24A4
SLC45A2
TCHH
TYR
TYRP1
WNT10A
ZEB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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