Article
The role of clinical variables, neuropsychological performance and SLC6A4 and COMT gene polymorphisms on the prediction of early response to fluoxetine in major depressive disorder.
Journal of affective disorders - 1 Dec 2010
Gudayol-Ferré Esteve, Herrera-Guzmán Ixchel, Camarena Beatriz, Cortés-Penagos Carlos, Herrera-Abarca Jorge E, Martínez-Medina Patricia, Cruz David, Hernández Sandra, Genis Alma, Carrillo-Guerrero Mariana Y, Avilés Reyes Rubén, Guàrdia-Olmos Joan
Abstract excerpt
INTRODUCTION: Major depressive disorder (MDD) is treated with antidepressants, but only between 50% and 70% of the patients respond to the initial treatment. Several authors suggested different factors that could predict antidepressant response, including clinical, psychophysiological, neuropsychological, neuroimaging, and genetic variables. However, these different predictors present poor prognostic sensitivity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.