Article
The Candida albicans ESCRT pathway makes Rim101-dependent and -independent contributions to pathogenesis.
Eukaryotic cell - 1 Aug 2010
Wolf Julie M, Johnson Diedre J, Chmielewski David, Davis Dana A
Abstract excerpt
Candida albicans is an opportunistic pathogen that colonizes diverse mucosal niches with distinct environmental characteristics. To adapt to these different sites, C. albicans must activate and attenuate a variety of signal transduction pathways. A mechanism of signal attenuation is through receptor endocytosis and subsequent vacuolar degradation, which requires the endosomal sorting complex required for...
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