Article
A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform.
Journal of affective disorders - 1 Dec 2010
Xu Yong, Liu Haiying, Li Fei, Sun Ning, Ren Yan, Liu Zhifen, Cao Xiaohua, Wang Yanfang, Liu Pozi, Zhang Kerang
Abstract excerpt
BACKGROUND: Growing evidence shows that the etiological causes and pathological processes underlying major depressive disorder (MDD) and schizophrenia (SCZ) overlap. Our previous study revealed a strong association between the polymorphism ss178077483 in the miRNA-30e precursor (pre-miR-30e) and the risk of SCZ. We thus hypothesized that this SCZ risk allele at the pre-miR-30e gene also confers risk of MDD....
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