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Nanog regulates primordial germ cell migration through Cxcr4b.

Stem cells (Dayton, Ohio) - 1 Sept 2010

Sánchez-Sánchez Ana Virginia, Camp Esther, Leal-Tassias Aránzazu, Atkinson Stuart P, Armstrong Lyle, Díaz-Llopis Manuel, Mullor José L

Abstract excerpt

Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct migration to the sites where the gonads develop. Several genes have been implicated in PGC specification and migration in vertebrates. Additionally, some of the genes associated with pluripotency, such as Oct4 and Nanog, are expressed in PGCs and gonads, suggesting a role for these genes in...

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PMID: 20578184
DOI: 10.1002/stem.469

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PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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