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Identification of Cross-Reactive Norovirus CD4 + T Cell Epitopes

24 Jun 2010

Abstract excerpt

Immune responses and the components of protective immunity following norovirus infection in humans are poorly understood. Although antibody responses following norovirus infection have been partially characterized, T cell responses in humans remain largely undefined. In contrast, T cells have been shown to be essential for viral clearance of mouse norovirus (MNV) infection. In this paper, we demonstrate that...

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PMID: 20573810
DOI: 10.1128/jvi.00727-10

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