Article
Transactivation of cytosolic alanine aminotransferase gene promoter by p300 and c-Myb.
Journal of molecular endocrinology - 1 Sept 2010
Anemaet Ida G, González Juan Diego, Salgado María C, Giralt Marina, Fernández Felipe, Baanante Isabel V, Metón Isidoro
Abstract excerpt
Alanine aminotransferase (Alt) provides a molecular link between carbohydrate and amino acid metabolism. In the cell context, the predominant Alt isozyme is located in the cytosol. To gain insight into the transcriptional regulation of the cytosolic alt gene (calt), we cloned and characterized the calt promoter from gilthead sea bream (Sparus aurata). Transient transfection of sea bass larvae cells with deleted...
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