Article
MCP-1 promotes mural cell recruitment during angiogenesis in the aortic ring model.
Angiogenesis - 1 Sept 2010
Aplin Alfred C, Fogel Eric, Nicosia Roberto F
Abstract excerpt
Rings of rat or mouse aorta embedded in collagen gels produce angiogenic outgrowths in response to the injury of the dissection procedure. Aortic outgrowths are composed of branching endothelial tubes and surrounding mural cells. Mural cells emerge following endothelial sprouting and gradually increase during the maturation of the neovessels. Treatment of aortic cultures with angiopoietin-1 (Ang-1), an angiogenic...
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