Article
Impact of monocyte chemoattractant protein-1 deficiency on cerebral aneurysm formation.
Stroke - 1 Mar 2009
Aoki Tomohiro, Kataoka Hiroharu, Ishibashi Ryota, Nozaki Kazuhiko, Egashira Kensuke, Hashimoto Nobuo
Abstract excerpt
BACKGROUND AND PURPOSE: Recent studies have suggested that chronic inflammation actively participates in cerebral aneurysm (CA) formation. Macrophages accumulate in CA walls and express proinflammatory genes promoting CA progression, but the molecular mechanisms of monocyte/macrophage recruitment into CA walls remain to be elucidated. METHODS: Monocyte chemoattractant protein-1 (MCP-1) expression in...
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