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Article

Predicting embryonic patterning using mutual entropy fitness and in silico evolution.

Development (Cambridge, England) - 1 Jul 2010

François Paul, Siggia Eric D

Abstract excerpt

During vertebrate embryogenesis, the expression of Hox genes that define anterior-posterior identity follows general rules: temporal colinearity and posterior prevalence. A mathematical measure for the quality or fitness of the embryonic pattern produced by a gene regulatory network is derived. U...

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Identifiers

PMID: 20570938
DOI: 10.1242/dev.048033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20570938-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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