Article
Phenotypic models of evolution and development: geometry as destiny.
Current opinion in genetics & development - 1 Dec 2012
François Paul, Siggia Eric D
Abstract excerpt
Quantitative models of development that consider all relevant genes typically are difficult to fit to embryonic data alone and have many redundant parameters. Computational evolution supplies models of phenotype with relatively few variables and parameters that allows the patterning dynamics to be reduced to a geometrical picture for how the state of a cell moves. The clock and wavefront model, that defines the...
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