Article
Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress.
Cellular signalling - 1 Oct 2010
Chhipa Rishi Raj, Wu Yue, Mohler James L, Ip Clement
Abstract excerpt
Androgen-independent prostate cancer usually develops as a relapse following androgen ablation therapy. Removing androgen systemically causes vascular degeneration and nutrient depletion of the prostate tumor tissue. The fact that the malignancy later evolves to androgen-independence suggests tha...
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