Interpretation of results with the 8-azaguanine resistance system in Salmonella typhimurium: no evidence for direct acting mutagenesis by 15-oxosteviol, a possible metabolite of steviol.

doi:10.1093/mutage/6.2.165

Back to search

Article

Interpretation of results with the 8-azaguanine resistance system in Salmonella typhimurium: no evidence for direct acting mutagenesis by 15-oxosteviol, a possible metabolite of steviol.

Mutagenesis - 1 Mar 1991

Procinska E, Bridges B A, Hanson J R

Abstract excerpt

15-Oxosteviol, postulated to be the mutagenic metabolite of steviol, was observed to be non-mutagenic in preliminary experiments using a number of different systems. Repetition of the original experiment in Salmonella TM677 failed to show any significant induction of 8-azaguanine resistant mutant...

Topics

Azaguanine
Dimethyl Sulfoxide
Diterpenes
Diterpenes, Kaurane
Drug Resistance, Microbial
Mutagenicity Tests
Mutation
Salmonella typhimurium

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.