Article
Natural selection in the chicken host identifies 3-deoxy-D-manno-octulosonic acid kinase residues essential for phosphorylation of Pasteurella multocida lipopolysaccharide.
Infection and immunity - 1 Sept 2010
Harper Marina, Cox Andrew D, St Michael Frank, Ford Mark, Wilkie Ian W, Adler Ben, Boyce John D
Abstract excerpt
Pasteurella multocida is the causative agent of a number of diseases in animals, including fowl cholera. P. multocida strains simultaneously express two lipopolysaccharide (LPS) glycoforms (glycoforms A and B) that differ only in their inner core structure. Glycoform A contains a single 3-deoxy-d-manno-octulosonic acid (Kdo) residue that is phosphorylated by the Kdo kinase, KdkA, whereas glycoform B contains two...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chickens
- Cholera
- Glycosyltransferases
- Lipopolysaccharides
- Molecular Sequence Data
- Mutation
- Pasteurella multocida