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Article

Identification of novel glycosyltransferases required for assembly of the Pasteurella multocida A:1 lipopolysaccharide and their involvement in virulence.

Infection and immunity - 1 Apr 2009

Boyce John D, Harper Marina, St Michael Frank, John Marietta, Aubry Annie, Parnas Henrietta, Logan Susan M, Wilkie Ian W, Ford Mark, Cox Andrew D, Adler Ben

Abstract excerpt

We previously determined the structure of the Pasteurella multocida Heddleston type 1 lipopolysaccharide (LPS) molecule and characterized some of the transferases essential for LPS biosynthesis. We also showed that P. multocida strains expressing truncated LPS display reduced virulence. Here, we have identified all of the remaining glycosyltransferases required for synthesis of the oligosaccharide extension of...

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Identifiers

PMID: 19168738
DOI: 10.1128/IAI.01144-08
PMCID: PMC2663145

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Source receipt: pubmed, retrieved 7 Sept 2026.

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