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Article

Transcriptome profiling indicates varied gene responses to Pasteurella multocida mutant infections in cattle.

PloS one - 1 Jan 2026

Ma Hao, Tatum Fred M, Briggs Robert E, Dassanayake Rohana P, Kendrick Tasia M, Casas Eduardo

Abstract excerpt

Pasteurella multocida is a pathogen that causes bovine respiratory disease, and the development of an effective vaccine is important for improving animal health. Live-attenuated vaccines induce a long-lasting immune response with minimal side effects. The objective of this study was to evaluate potential live vaccine candidates from three P. multocida mutants produced by separately disrupting the genes of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41615958
DOI: 10.1371/journal.pone.0341813
PMCID: PMC12857936

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