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Article

CDKN1C (p57KIP2) mRNA expression in human retinoblastomas.

Ophthalmic genetics - 1 Sept 2010

Madhavan Jagadeesan, Mallikarjuna Kandalam, Vikas Khetan, George Ronnie, Bremner Rod, Kumaramanickavel Govindasamy

Abstract excerpt

PURPOSE: Quantify cyclin dependent kinase inhibitor 1C (CDKN1C or p57KIP2) mRNA levels in human retinoblastoma tumors (RB) and associate with disease phenotype. METHODS: CDKN1C mRNA expression was quantified in 55 RB, 3 retinoblastoma cell lines, and 12 control retinas by real time PCR. Localization of CDKN1C protein was confirmed by immunohistochemistry. Tumor CDKN1C expression levels were correlated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20565244
DOI: 10.3109/13816810.2010.490544

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