Article
KIF14 and E2F3 mRNA expression in human retinoblastoma and its phenotype association.
Molecular vision - 1 Jan 2009
Madhavan Jagadeesan, Mitra Moutushy, Mallikarjuna Kandalam, Pranav Oberoi, Srinivasan Ramalingam, Nagpal Amit, Venkatesan Perumal, Kumaramanickavel Govindasamy
Abstract excerpt
PURPOSE: We quantified mRNA expression of candidate genes for proliferation (KIF14 and E2F3) in a large retinoblastoma tumor cohort and associated with disease phenotype. METHODS: KIF14 and E2F3 mRNA expression was quantified by real time PCR in 57 retinoblastoma (RB) tumors, 3 RB cell lines, and control samples that included 4 each fetal, age-matched, adult retinas. Immunohistochemistry was done to confirm KIF14...
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