Article
Genetic variability of the small t antigen of the novel KI, WU and MC polyomaviruses.
Archives of virology - 1 Sept 2010
Ciccozzi Massimo, Babakir-Mina Muhammed, Lo Presti Alessandra, Farchi Francesca, Zehender Gianguglielmo, Ebranati Erika, Perno Carlo Federico, Ciotti Marco
Abstract excerpt
Recently, three novel human polyomaviruses were discovered: KIPyV, WUPyV and MCPyV. To study the genetic variability of these viruses, an evolutionary analysis of the large T antigen, small t antigen, VP1, VP2 and VP3 genes was carried out. Of the genes analyzed, only the small t antigen of KIPyV and MCPyV was found to be under statistically supported selective pressure. In KIPyV, 31 selected sites were found...
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