Article
Accurate Genomic Prediction of Human Height.
Genetics - 1 Oct 2018
Lello Louis, Avery Steven G, Tellier Laurent, Vazquez Ana I, de Los Campos Gustavo, Hsu Stephen D H
Abstract excerpt
We construct genomic predictors for heritable but extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning). The constructed predictors explain, respectively, ∼40, 20, and 9% of total variance for the three traits, in data not used for training. For example, predicted heights correlate ∼0.65 with...
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