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Kinetic Evidence for the Presence of Putative Germination Receptors in C lostridium difficile Spores

21 Jun 2010

Abstract excerpt

Clostridium difficile is a spore-forming bacterium that causes Clostridium difficile-associated disease (CDAD). Intestinal microflora keeps C. difficile in the spore state and prevents colonization. Following antimicrobial treatment, the microflora is disrupted, and C. difficile spores germinate in the intestines. The resulting vegetative cells are believed to fill empty niches left by the depleted microbial...

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PMID: 20562307
DOI: 10.1128/jb.00488-10

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