Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unbiased and locally efficient estimation of genetic effect on quantitative trait in the presence of population admixture.

Biometrics - 1 Jun 2011

Wang Yuanjia, Yang Qiong, Rabinowitz Daniel

Abstract excerpt

Population admixture can be a confounding factor in genetic association studies. Family-based methods (Rabinowitz and Larid, 2000, Human Heredity 50, 211-223) have been proposed in both testing and estimation settings to adjust for this confounding, especially in case-only association studies. Th...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Confounding Factors, Epidemiologic
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Lipoproteins, LDL

Share to Models, Genetic

Share to Models, Statistical

Share to Quantitative Trait, Heritable

Source

Open in PubMed Open full text

Identifiers

PMID: 20560930
DOI: 10.1111/j.1541-0420.2010.01454.x
PMCID: PMC2948587

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20560930-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unbiased and locally efficient estimation of genetic effect on quantitative trait in the presence of population admixture.PMID 20560930Read ↗

A unified association analysis approach for family and unrelated samples correcting for stratification.Semantic proximity Read ↗

Optimum study design for detecting imprinting and maternal effects based on partial likelihood.Semantic proximity Read ↗

A robust and powerful two-step testing procedure for local ancestry adjusted allelic association analysis in admixed populations.Semantic proximity Read ↗

Unbiased discordant sib-pair tests when parental genotypes are missing.Semantic proximity Read ↗

Efficient inference of local ancestry.Semantic proximity Read ↗

A hybrid bayesian approach for genome-wide association studies on related individuals.Semantic proximity Read ↗

Genetic association tests for family data with missing parental genotypes: a comparison.Semantic proximity Read ↗

The role of local ancestry adjustment in association studies using admixed populations.Semantic proximity Read ↗

On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies.Semantic proximity Read ↗

Exact family-based association tests for biallelic data.Semantic proximity Read ↗

Testing genetic association with rare variants in admixed populations.Semantic proximity Read ↗

Estimation of individual admixture: analytical and study design considerations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.