Article
Different outcomes of experimental leptospiral infection in mouse strains with distinct genotypes.
Journal of medical microbiology - 1 Sept 2010
Santos Cleiton S, Macedo Júlio O, Bandeira Mauricio, Chagas-Junior Adenizar D, McBride Alan J A, McBride Flávia W C, Reis Mitermayer G, Athanazio Daniel A
Abstract excerpt
The mouse disease model has the advantage of a broad array of immunological and genetic tools available for basic research. Some studies on transgenic and/or mutant mouse strains as models for experimental leptospirosis have been reported; however, the wider use of such models is hampered by a poor understanding of the outcome of experimental leptospiral infection among the different mouse strains available....
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