Article
Clinical relevance and diversity of two homologous genes encoding glycosyltransferases in Helicobacter pylori.
Journal of clinical microbiology - 1 Aug 2010
Oleastro Mónica, Santos Andrea, Cordeiro Rita, Nunes Baltazar, Mégraud Francis, Ménard Armelle
Abstract excerpt
Helicobacter pylori is known to be a major cause of peptic ulceration. The jhp0562 gene, encoding a glycosyltransferase involved in the synthesis of the lipopolysaccharide, was associated with peptic ulcer disease (PUD) in children. The beta-(1,3)-galactosyltransferase [beta-(1,3)GalT] gene (jhp0563), involved in Lewis (Le) antigen expression, is highly similar to jhp0562. The clinical significance and diversity...
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