A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

doi:10.1038/ng2075

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Article

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

Nature genetics - 1 Jul 2007

Hunter David J, Kraft Peter, Jacobs Kevin B, Cox David G, Yeager Meredith, Hankinson Susan E, Wacholder Sholom, Wang Zhaoming, Welch Robert, Hutchinson Amy, Wang Junwen, Yu Kai, Chatterjee Nilanjan, Orr Nick, Willett Walter C, Colditz Graham A, Ziegler Regina G, Berg Christine D, Buys Saundra S, McCarty Catherine A, Feigelson Heather Spencer, Calle Eugenia E, Thun Michael J, Hayes Richard B, Tucker Margaret, Gerhard Daniela S, Fraumeni Joseph F, Hoover Robert N, Thomas Gilles, Chanock Stephen J

Abstract excerpt

We conducted a genome-wide association study (GWAS) of breast cancer by genotyping 528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast cancer and 1,142 controls. We identified four SNPs in intron 2 of FGFR2 (which encodes a receptor tyrosine kinase and is amplifie...

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PMID: 17529973
DOI: 10.1038/ng2075
PMCID: PMC3493132

Genes

FGFR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17529973-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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