Article
Neurofibromatosis type 2: molecular and clinical analyses in Argentine sporadic and familial cases.
Neuroscience letters - 9 Aug 2010
Ferrer Marcela, Schulze Aljoscha, Gonzalez Sergio, Ferreiro Verónica, Ciavarelli Patricia, Otero José, Giliberto Florencia, Basso Armando, Szijan Irene
Abstract excerpt
Neurofibromatosis 2 is a familial syndrome characterized by the development of schwannomas, meningiomas and ependymomas. Most of them are benign however, their location in the nervous system has harmful effects on important cranial and spinal structures. These tumors are developed as the outcome of NF2 gene (22q12) inactivation. The NF2 protein, merlin or schwannomin belongs to the Ezrin, Radixin, Moesin (ERM)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.