Article
REVIEW: Genome-wide findings in schizophrenia and the role of gene-environment interplay.
CNS neuroscience & therapeutics - 1 Oct 2010
Van Winkel Ruud, Esquivel Gabriel, Kenis Gunter, Wichers Marieke, Collip Dina, Peerbooms Odette, Rutten Bart, Myin-Germeys Inez, Van Os Jim
Abstract excerpt
The recent advent of genome-wide mass-marker technology has resulted in renewed optimism to unravel the genetic architecture of psychotic disorders. Genome-wide association studies have identified a number of common polymorphisms robustly associated with schizophrenia, in ZNF804A, transcription factor 4, major histocompatibility complex, and neurogranin. In addition, copy number variants (CNVs) in 1q21.1, 2p16.3,...
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