Article
Genetic polymorphism of the C-reactive protein (CRP) gene and a deep infection focus determine maximal serum CRP level in Staphylococcus aureus bacteremia.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Sept 2010
Mölkänen T, Rostila A, Ruotsalainen E, Alanne M, Perola M, Järvinen A
Abstract excerpt
C-reactive protein (CRP) is widely used in early detection of sepsis or organ dysfunction. Several single nucleotide polymorphisms (SNPs) in the CRP gene are shown to be associated with variability of basal CRP. To clarify the effect of these SNPs to CRP response in systemic infections, we compared genetic and clinical data on patients with Staphylococcus aureus bacteremia (SAB). Six SNPs in the CRP gene region...
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