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Article

The effect on intracytoplasmic sperm injection outcome of genotype, male germ cell stage and freeze-thawing in mice.

PloS one - 11 Jun 2010

Ogonuki Narumi, Mori Manami, Shinmen Akie, Inoue Kimiko, Mochida Keiji, Ohta Akihiko, Ogura Atsuo

Abstract excerpt

BACKGROUND: Intracytoplasmic sperm injection (ICSI) has been widely used to study the mechanisms of mammalian fertilization and to rescue male-factor infertility in humans and animals. However, very few systematic analyses have been conducted to define factors affecting the efficiency of ICSI. In this study, we undertook a large-scale series of ICSI experiments in mice to define the factors that might affect...

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Source

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Identifiers

PMID: 20552034
DOI: 10.1371/journal.pone.0011062
PMCID: PMC2884038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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