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Article

Infertility and male mating behavior deficits associated with Pde1c in Drosophila melanogaster.

Genetics - 1 Sept 2010

Morton David B, Clemens-Grisham Rachel, Hazelett Dennis J, Vermehren-Schmaedick Anke

Abstract excerpt

Pde1c is a calcium/calmodulin-regulated, dual-specificity cyclic nucleotide phosphodiesterase. We have used a transposon insertion line to investigate the physiological function of Pde1c in Drosophila melanogaster and to show that the insertion leads to male sterility and male mating behavior defects that include reduced copulation rates. Sterility appears to be primarily due to elimination of sperm from the...

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Identifiers

PMID: 20551439
DOI: 10.1534/genetics.110.118018
PMCID: PMC2940284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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