A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical <i>Staphylococcus aureus</i> strains

Abstract excerpt

Staphylococcus aureus is an versatile pathogen that can cause life-threatening infections. Depending on the clinical setting, up to 50% of S. aureus infections are caused by methicillin-resistant strains (MRSA) that in most cases are resistant to many other antibiotics, making treatment difficult. The emergence of community-acquired MRSA drastically changed the picture by increasing the risk of MRSA infections....

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