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Article

Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation.

Neurobiology of disease - 1 Sept 2010

Rodríguez-Navarro Jose A, Rodríguez Laura, Casarejos María J, Solano Rosa M, Gómez Ana, Perucho Juan, Cuervo Ana María, García de Yébenes Justo, Mena María A

Abstract excerpt

Tauopathies are neurodegenerative diseases, sporadic or familial, mainly characterized by dementia and parkinsonism associated to atrophy of the frontotemporal cortex and the basal ganglia, with deposition of abnormal tau in brain. Hereditary tauopathies are related with mutations of the tau gene. Up to the present, these diseases have not been helped by any disease-modifying treatment, and patients die a few...

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PMID: 20546895
DOI: 10.1016/j.nbd.2010.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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