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Article

Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5).

Diabetic medicine : a journal of the British Diabetic Association - 1 Jun 2010

Zampetti S, Spoletini M, Petrone A, Capizzi M, Arpi M L, Tiberti C, Di Pietro S, Bosi E, Pozzilli P, Giorgino F, Buzzetti R

Abstract excerpt

AIMS: We previously demonstrated the presence of two different populations among adult-onset autoimmune diabetes (latent autoimmume diabetes of adults; LADA) having high or low titre of antibodies to glutamic acid decarboxylase (GADA). The transcription factor 7-like 2 (TCF7L2) gene has been recognized as the major gene associated with Type 2 diabetes. The aim of the present study was to evaluate whether the...

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Identifiers

PMID: 20546291
DOI: 10.1111/j.1464-5491.2010.02997.x

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