Article
Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes.
BMC medicine - 25 Apr 2017
Mishra Rajashree, Chesi Alessandra, Cousminer Diana L, Hawa Mohammad I, Bradfield Jonathan P, Hodge Kenyaita M, Guy Vanessa C, Hakonarson Hakon, Mauricio Didac, Schloot Nanette C, Yderstræde Knud B, Voight Benjamin F, Schwartz Stanley, Boehm Bernhard O, Leslie Richard David, Grant Struan F A
Abstract excerpt
BACKGROUND: In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as 'latent autoimmune diabetes in adults' (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci in a large cohort of LADA cases to assess where LADA is situated relative to these two well-characterized, classic forms of diabetes. METHODS: We tested the...
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