Article
Single nucleotide transcription factor 7-like 2 (TCF7L2) gene polymorphisms in antiislet autoantibody-negative patients at onset of diabetes.
The Journal of clinical endocrinology and metabolism - 1 Feb 2009
Yu Jeesuk, Steck Andrea K, Babu Sunanda, Yu Liping, Miao Dongmei, McFann Kim, Hutton John, Eisenbarth George S, Klingensmith Georgeanna
Abstract excerpt
CONTEXT: There is controversy as to whether type 2 diabetes genetic susceptibility contributes to type 1 diabetes, and it is not known what proportion of islet autoantibody-negative new onset subjects have type 2 diabetes risk alleles. OBJECTIVES: We designed this study to evaluate whether two type 2 diabetes-associated single nucleotide polymorphisms (SNPs) of transcription factor 7-like 2 (TCF7L2) gene are...
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