Article
Baff serum level predicts time to first treatment in early chronic lymphocytic leukemia.
European journal of haematology - 1 Oct 2010
Molica Stefano, Digiesi Giovanna, Battaglia Caterina, Cutrona Giovanna, Antenucci Anna, Molica Matteo, Giannarelli Diana, Sperduti Isabella, Gentile Massimo, Morabito Fortunato, Ferrarini Manlio
Abstract excerpt
We analyzed the correlation between well-established biological parameters of prognostic relevance in B-cell chronic lymphocytic leukemia (CLL) [i.e. mutational status of the immunoglobulin heavy chain variable region (IgVH), ZAP-70 and CD38 expression] and serum levels of B cell-activating factor (BAFF of the TNF family) by evaluating the impact of these variables on the time to first treatment (TFT) in a series...
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