Article
Leishmania: conserved evolution--diverse diseases.
Trends in parasitology - 1 Mar 2008
Lynn Miriam A, McMaster W Robert
Abstract excerpt
The landmark completion of the Leishmania major genome sequence and the recent publication of the L. infantum and L. braziliensis genomes revealed the surprising result that, although separated by 15-50 million years of evolution, the Leishmania genomes are highly conserved and have less than 1% species-specific genes. Yet, these three species of Leishmania cause distinctive and diverse diseases in humans. Here,...
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