Article
In vitro vs in silico detected SNPs for the development of a genotyping array: what can we learn from a non-model species?
PloS one - 9 Jun 2010
Lepoittevin Camille, Frigerio Jean-Marc, Garnier-Géré Pauline, Salin Franck, Cervera María-Teresa, Vornam Barbara, Harvengt Luc, Plomion Christophe
Abstract excerpt
BACKGROUND: There is considerable interest in the high-throughput discovery and genotyping of single nucleotide polymorphisms (SNPs) to accelerate genetic mapping and enable association studies. This study provides an assessment of EST-derived and resequencing-derived SNP quality in maritime pine (Pinus pinaster Ait.), a conifer characterized by a huge genome size ( approximately 23.8 Gb/C). METHODOLOGY/PRINCIPAL...
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