Article
Low cut-off values increase diagnostic performance of protein S assays.
Thrombosis and haemostasis - 1 Sept 2010
Mulder René, Ten Kate Min Ki, Kluin-Nelemans Hanneke C, Mulder André B
Abstract excerpt
Conflicting data have been reported on the accuracy of protein S (PS) assays for detection of hereditary PS deficiency. In this study we assessed the diagnostic performance of two total PS antigen assays, four free PS assays and three PS activity assays in a group of 28 heterozygous carriers of mutations in PROS1 and 165 control subjects. Several control groups were formed, one of healthy volunteers and - because...
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